Epicutaneous allergen administration without antigen delivery device induces local T cell response and alleviates food allergic enteropathy

• Mamiko Morinaga,
• Haruyo Nakajima-Adachi,
• Erika Hiraide,
• Noriko Kitamura,
• Osamu Kaminuma,
• Takachika Hiroi,
• Katsuyo Ohashi-Doi,
• Satoshi Hachimura

Affiliations

Mamiko Morinaga

Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan

Haruyo Nakajima-Adachi

Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan

Erika Hiraide

Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan

Noriko Kitamura

Department of Genome Medicine, Allergy and Immunology Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan

Osamu Kaminuma

Department of Genome Medicine, Allergy and Immunology Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan; Department of Disease Model, Research Institute of Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan

Takachika Hiroi

Department of Genome Medicine, Allergy and Immunology Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan

Katsuyo Ohashi-Doi

Research Laboratories, Torii Pharmaceutical Co., Ltd., Tokyo, Japan

Satoshi Hachimura

Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan; Corresponding author. Research Center for Food Safety Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.