Generating receptive endometrium in Asherman′s syndrome

Abstract

Intrauterine administration of bone marrow stem/progenitor cells to a woman with thin endometrium refractory to estrogen stimulation regenerated her endometrium sufficiently to support a pregnancy. Or was it local endometrial damage induced by concurrent curettage that stimulated endogenous endometrial stem/progenitor cells into action? Or both?

Keywords

• Adult stem cells
• Asherman′s syndrome
• bone marrow
• endometrial stem cells
• endometrium
• regeneration
• transplant