MAJOR INTERCELLULAR INTERACTIONS AT THE T CELL ACTIVATION IN RENAL TRANSPLANT REJECTION

Abstract

Currently, an organ rejection is a leading cause of kidney transplants loss. Effective therapy is impossible without a clear understanding of the rejection mechanisms. In this paper, we summarize the views of domestic and foreign authors on the role of T cell activation in kidney transplant rejection.

Keywords

• co-stimulation
• cell activation
• immune response
• т cells
• antigen-presenting cells