Nature Communications (Oct 2019)

Electro-optic imaging enables efficient wide-field fluorescence lifetime microscopy

  • Adam J. Bowman,
  • Brannon B. Klopfer,
  • Thomas Juffmann,
  • Mark A. Kasevich

DOI
https://doi.org/10.1038/s41467-019-12535-5
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 8

Abstract

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Nanosecond imaging techniques, such as fluorescence lifetime imaging microscopy (FLIM), are limited by low efficiency of current detectors. Here, the authors implement an electro-optic approach using Pockels cells for wide-field image gating and demonstrate high throughput FLIM on standard camera sensors.