Correction of affective and cognitive disorders in epileptic patients and the value of lamotrigine

Abstract

The paper characterizes an association of cognitive and affective disorders in epilepsy, which may be a cause of worse quality of life, social dysadaptation, and disability. In this connection, it is imperative to choose correct antiepileptic drugs (AEDs). Groups of AEDs with different modes of action are considered, among which, lamotrigine that is noted for its unique profile of not only antiepileptic, but also psychotropic properties is given much attention.

Keywords

• depression
• dysphoria
• anxiety disorders
• tonic-clonic seizures
• gabaergic activity