Squamous Cell Carcinoma of Nasofacial Groove

Abstract

Abstract Introduction: Cutaneous squamous cell carcinoma is a malignant tumour that develops in the squamous cells that make up the middle and outer layers of the skin. It often forms on parts of skin frequently exposed to sunlight. It is usually not life-threatening, though it can be aggressive causing serious complications. However, nasofacial groove is a very uncommon area for the origin of squamous cell carcinoma. Case Report: A 65-year-old housewife with hypertension and type 2 Diabetes Mellitus presented with painless swelling over right nasofacial groove for last 5 months which was insidious in onset, gradually progressive to reach the present size. On clinical examination, oval, localized, non-tender, hard 2cm x 2cm swelling was found over right nasofacial groove. Diagnostic nasal endoscopy was within normal limit. Computed Tomography showed a well-defined heterogenous oval mass over the right maxilla extending over right nasofacial region. Aspiration cytology yielded a few round to oval epithelial cells and fibrous stroma in a haemorrhagic background. A provisional diagnosis of appendageal tumour of nasofacial groove was made. Surgical excision was done under general anaesthesia. Gross examination showed predominantly solid and grey mass. Microscopically the lesion showed features of moderately differentiated squamous cell carcinoma. Further Total Maxillectomy with Modified Radical Neck Dissection type 3 has been done. Discussion: Squamous cell carcinoma of the skin may mimic nasolabial cyst. Hence the diagnosis should be kept in mind while dealing with a suspicious case of nasolabial cyst.

Keywords

• Squamous cell carcinoma
• Nasofacial groove
• Midface swelling
• Swelling over maxilla
• Malignant tumour
• Epidermal keratinocytes