Nature Communications (Oct 2018)

Megahertz serial crystallography

  • Max O. Wiedorn,
  • Dominik Oberthür,
  • Richard Bean,
  • Robin Schubert,
  • Nadine Werner,
  • Brian Abbey,
  • Martin Aepfelbacher,
  • Luigi Adriano,
  • Aschkan Allahgholi,
  • Nasser Al-Qudami,
  • Jakob Andreasson,
  • Steve Aplin,
  • Salah Awel,
  • Kartik Ayyer,
  • Saša Bajt,
  • Imrich Barák,
  • Sadia Bari,
  • Johan Bielecki,
  • Sabine Botha,
  • Djelloul Boukhelef,
  • Wolfgang Brehm,
  • Sandor Brockhauser,
  • Igor Cheviakov,
  • Matthew A. Coleman,
  • Francisco Cruz-Mazo,
  • Cyril Danilevski,
  • Connie Darmanin,
  • R. Bruce Doak,
  • Martin Domaracky,
  • Katerina Dörner,
  • Yang Du,
  • Hans Fangohr,
  • Holger Fleckenstein,
  • Matthias Frank,
  • Petra Fromme,
  • Alfonso M. Gañán-Calvo,
  • Yaroslav Gevorkov,
  • Klaus Giewekemeyer,
  • Helen Mary Ginn,
  • Heinz Graafsma,
  • Rita Graceffa,
  • Dominic Greiffenberg,
  • Lars Gumprecht,
  • Peter Göttlicher,
  • Janos Hajdu,
  • Steffen Hauf,
  • Michael Heymann,
  • Susannah Holmes,
  • Daniel A. Horke,
  • Mark S. Hunter,
  • Siegfried Imlau,
  • Alexander Kaukher,
  • Yoonhee Kim,
  • Alexander Klyuev,
  • Juraj Knoška,
  • Bostjan Kobe,
  • Manuela Kuhn,
  • Christopher Kupitz,
  • Jochen Küpper,
  • Janine Mia Lahey-Rudolph,
  • Torsten Laurus,
  • Karoline Le Cong,
  • Romain Letrun,
  • P. Lourdu Xavier,
  • Luis Maia,
  • Filipe R. N. C. Maia,
  • Valerio Mariani,
  • Marc Messerschmidt,
  • Markus Metz,
  • Davide Mezza,
  • Thomas Michelat,
  • Grant Mills,
  • Diana C. F. Monteiro,
  • Andrew Morgan,
  • Kerstin Mühlig,
  • Anna Munke,
  • Astrid Münnich,
  • Julia Nette,
  • Keith A. Nugent,
  • Theresa Nuguid,
  • Allen M. Orville,
  • Suraj Pandey,
  • Gisel Pena,
  • Pablo Villanueva-Perez,
  • Jennifer Poehlsen,
  • Gianpietro Previtali,
  • Lars Redecke,
  • Winnie Maria Riekehr,
  • Holger Rohde,
  • Adam Round,
  • Tatiana Safenreiter,
  • Iosifina Sarrou,
  • Tokushi Sato,
  • Marius Schmidt,
  • Bernd Schmitt,
  • Robert Schönherr,
  • Joachim Schulz,
  • Jonas A. Sellberg,
  • M. Marvin Seibert,
  • Carolin Seuring,
  • Megan L. Shelby,
  • Robert L. Shoeman,
  • Marcin Sikorski,
  • Alessandro Silenzi,
  • Claudiu A. Stan,
  • Xintian Shi,
  • Stephan Stern,
  • Jola Sztuk-Dambietz,
  • Janusz Szuba,
  • Aleksandra Tolstikova,
  • Martin Trebbin,
  • Ulrich Trunk,
  • Patrik Vagovic,
  • Thomas Ve,
  • Britta Weinhausen,
  • Thomas A. White,
  • Krzysztof Wrona,
  • Chen Xu,
  • Oleksandr Yefanov,
  • Nadia Zatsepin,
  • Jiaguo Zhang,
  • Markus Perbandt,
  • Adrian P. Mancuso,
  • Christian Betzel,
  • Henry Chapman,
  • Anton Barty

DOI
https://doi.org/10.1038/s41467-018-06156-7
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 11

Abstract

Read online

The new European X-Ray Free-Electron Laser (EuXFEL) is the first XFEL that generates X-ray pulses with a megahertz inter-pulse spacing. Here the authors demonstrate that high-quality and damage-free protein structures can be obtained with the currently available 1.1 MHz repetition rate pulses using lysozyme as a test case and furthermore present a β-lactamase structure.