Late Worsening of COVID-19 Pneumonia: Successful Treatment with Ruxolitinib and Steroid

Abstract

We describe the case of a patient hospitalized for the second time in a month due to delayed worsening of lung lesions in COVID-19 infection without bacterial superinfection. He was treated with hydroxychloroquine, IV dexamethasone and ruxolitinib with rapid improvement of respiratory failure; 1 month after the second discharge, maintaining low-dose oral prednisone, lung consolidations were significantly reduced on control CT.

Keywords

• covid-19
• ruxolitinib
• janus kinase inhibitors