Intermittent theta-burst stimulation in aphasia caused by right side cerebral lesions after stroke: A case report with 2-year follow-up
Haozheng Li,
Shunjuan Fan,
Yi Wu,
Dongxiang Fang,
Ruiping Hu,
Rongrong Lu
Affiliations
Haozheng Li
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, 200040, Shanghai, China; National Center for Neurological Disorders, 20040, Shanghai, China
Shunjuan Fan
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, 200040, Shanghai, China; National Center for Neurological Disorders, 20040, Shanghai, China
Yi Wu
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, 200040, Shanghai, China; National Center for Neurological Disorders, 20040, Shanghai, China
Dongxiang Fang
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, 200040, Shanghai, China; National Center for Neurological Disorders, 20040, Shanghai, China
Ruiping Hu
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, 200040, Shanghai, China; National Center for Neurological Disorders, 20040, Shanghai, China; Corresponding author. Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, 200040, Shanghai, China
Rongrong Lu
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, 200040, Shanghai, China; National Center for Neurological Disorders, 20040, Shanghai, China; Corresponding author. National Center for Neurological Disorders, 20040, Shanghai, China.
Background and objectives: This case report investigates the application of intermittent Theta-Burst Stimulation (iTBS) in aphasia rehabilitation following a right hemisphere stroke. Case presentation: A 52-year-old Chinese male with Broca's aphasia post-stroke was treated with iTBS. His progress was evaluated using Functional Near-Infrared Spectroscopy (fNIRS) and behavioral assessments. Significant language function improvement was noted, with fNIRS showing increased activation in right hemisphere language-related cortical areas and altered functional connectivity patterns. Conclusion: The findings indicate that iTBS is effective in facilitating language recovery in right hemisphere stroke-induced aphasia, highlighting the importance of personalized neurorehabilitation strategies. Despite focusing on a single case, the study contributes to understanding neural plasticity mechanisms in right hemisphere stroke-induced aphasia.
