PLoS ONE (Jan 2024)

Factors associated with frequent buprenorphine / naloxone initiation in a national survey of Canadian emergency physicians.

  • Nathalie MacKinnon,
  • Daniel Lane,
  • Frank Scheuermeyer,
  • Janusz Kaczorowski,
  • Kathryn Dong,
  • Aaron M Orkin,
  • Raoul Daoust,
  • Jessica Moe,
  • Gary Andolfatto,
  • Michelle Klaiman,
  • Justin Yan,
  • Justin J Koh,
  • Kathryn Crowder,
  • Paul Atkinson,
  • David Savage,
  • James Stempien,
  • Floyd Besserer,
  • Jason Wale,
  • Andrew Kestler

DOI
https://doi.org/10.1371/journal.pone.0297084
Journal volume & issue
Vol. 19, no. 2
p. e0297084

Abstract

Read online

ObjectiveTo identify individual and site-related factors associated with frequent emergency department (ED) buprenorphine/naloxone (BUP) initiation. BUP initiation, an effective opioid use disorder (OUD) intervention, varies widely across Canadian EDs.MethodsWe surveyed emergency physicians in 6 Canadian provinces from 2018 to 2019 using bilingual paper and web-based questionnaires. Survey domains included BUP-related practice, demographics, attitudes toward BUP, and site characteristics. We defined frequent BUP initiation (the primary outcome) as at least once per month, high OUD prevalence as at least one OUD patient per shift, and high OUD resources as at least 3 out of the following 5 resources: BUP initiation pathways, BUP in ED, peer navigators, accessible addiction specialists, and accessible follow-up clinics. We excluded responses from sites with ResultsWe excluded 3 responses for missing BUP initiation frequency and 9 for low response rate at one ED. Of the remaining 649 respondents from 34 EDs, 374 (58%) practiced in metropolitan areas, 384 (59%) reported high OUD prevalence, 312 (48%) had high OUD resources, and 161 (25%) initiated BUP frequently. Age, gender, board certification and years in practice were not associated with frequent BUP initiation. Site-specific factors were associated with frequent BUP initiation (high OUD resources [OR 6.91], high OUD prevalence [OR 4.45], and metropolitan location [OR 2.39],) as were individual attitudinal factors (willingness, confidence, and responsibility to initiate BUP.) Similar associations persisted in the high OUD prevalence subgroup.ConclusionsIndividual attitudinal and site-specific factors were associated with frequent BUP initiation. Training to increase physician confidence and increasing OUD resources could increase BUP initiation and benefit ED patients with OUD.