An alternative pathway of enteric PEDV dissemination from nasal cavity to intestinal mucosa in swine

Yuchen Li; Qingxin Wu; Lulu Huang; Chen Yuan; Jialu Wang; Qian Yang

doi:10.1038/s41467-018-06056-w

Nature Communications (Sep 2018)

An alternative pathway of enteric PEDV dissemination from nasal cavity to intestinal mucosa in swine

Yuchen Li,
Qingxin Wu,
Lulu Huang,
Chen Yuan,
Jialu Wang,
Qian Yang

Affiliations

Yuchen Li: MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University
Qingxin Wu: MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University
Lulu Huang: MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University
Chen Yuan: MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University
Jialu Wang: MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University
Qian Yang: MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University

DOI: https://doi.org/10.1038/s41467-018-06056-w
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 14

Abstract

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Outbreaks of porcine epidemic diarrhea virus (PEDV) have seriously affected pig farms around the world. Here, Li et al. show that PEDV can cause disease in piglets when inoculated by nasal spray, and provide insights into the cellular mechanisms underlying PEDV dissemination within the host.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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