The role of prophylaxis of bacterial infections in children with acute leukemia/non-Hodgkin lymphoma

Abstract

Infections represent a well-known complication of antineoplastic chemotherapy that may cause delay of treatment, with alteration of the antineoplastic program and dose-intensity, or even the death of a patient that could heal from his/her neoplasia. Bacterial infections are a major cause of morbidity and mortality in patients who are neutropenic following chemotherapy for malignancy. Therefore a program of antibiotic prophylaxis for febrile neutropenia may be considered in the management strategy of cancer patients.

Keywords

• acute leukemia, non-Hodgkin lymphoma, bacterial infections, prophylaxis