Canadian Journal of Infectious Diseases and Medical Microbiology (Jan 2009)

Profile of Serogroup Y Meningococcal Infections in Canada: Implications for Vaccine Selection

  • Nicole Le Saux,
  • Julie A Bettinger,
  • Susan Wootton,
  • Scott A Halperin,
  • Wendy Vaudry,
  • David W Scheifele,
  • Raymond Tsang

Journal volume & issue
Vol. 20, no. 4
pp. e130 – e134


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Canada is a leader in establishing routine infant immunization programs against meningococcal C disease. Currently, all provinces have routine programs to provide meningococcal C conjugate vaccines to infants and children. The result of the existing programs has been a decrease in serogroup C incidence. The second most common vaccine-preventable serogroup in Canada is serogroup Y, the incidence of which has been stable. The availability of a quadrivalent conjugate vaccine against serogroups A, C, Y and W135 focuses attention on serogroup Y disease as it becomes relatively more prominent as a cause of vaccine-preventable invasive meningococcal disease. This vaccine was licensed in November 2006 but is not routinely used except in Nunavut, New Brunswick and Prince Edward Island. To allow a better understanding of the ‘value added’ by a serogroup Y-containing vaccine, it is necessary to have a contemporary profile of Y disease in Canada. In the present paper, recent surveillance data on invasive meningococcal disease across Canada are summarized.