Recurrent pneumonia in a child with Jacobsen syndrome and common variable immune deficiency

Abstract

Key Clinical Message Recurrent severe respiratory infections in Jacobsen syndrome (JS) are unusual and should prompt evaluation of the immune system. A variety of immune defects have been reported in JS and intravenous immune globulin (IVIG) treatment reduces severe infections.

Keywords

• CVID
• genetics and genomics
• immunology
• Jacobsen Syndrome
• pediatric pulmonology
• pneumonia