The Effects of Inhaled β-Adrenergic Agonists in Transient Tachypnea of the Newborn

Esengul Keleş MD; Arzu Gebeşçe MD; Mehmet Demirdöven MD; Hamza Yazgan MD; Bülent Baştürk MD; Alparslan Tonbul MD

doi:10.1177/2333794X16645258

Global Pediatric Health (May 2016)

The Effects of Inhaled β-Adrenergic Agonists in Transient Tachypnea of the Newborn

Esengul Keleş MD,
Arzu Gebeşçe MD,
Mehmet Demirdöven MD,
Hamza Yazgan MD,
Bülent Baştürk MD,
Alparslan Tonbul MD

Affiliations

Esengul Keleş MD: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul
Arzu Gebeşçe MD: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul
Mehmet Demirdöven MD: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul
Hamza Yazgan MD: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul
Bülent Baştürk MD: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul
Alparslan Tonbul MD: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul

DOI: https://doi.org/10.1177/2333794X16645258
Journal volume & issue: Vol. 3

Abstract

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Aim . To investigate the efficacy of an inhaled β-adrenergic agonists in transient tachypnea of the newborn (TTN). Method . We retrospectively analyzed a cohort of 51 term infants (Group 1) and 37 term infants (Group 2) monitored in the newborn intensive care unit diagnosed with TTN. Infants in Group 1 received humidified oxygen alone, and infants in Group 2 were administered the inhaled β-2 agonist plus humidified oxygen. Results . TTN clinical respiratory assessment, respiratory rate, oxygen saturation values, need for supplemental oxygen therapy, blood gas PH, PO 2 , and duration of hospitalization were significantly improved in infants in Group 2 as compared with infants in Group 1 ( P .05). Conclusion . Inhaled β-adrenergic agonist added to humidified oxygen was found to improve clinical and laboratory parameters. We believe that further studies should be conducted with larger groups to demonstrate the efficacy of β-2 agonists in TTN patients.

Published in Global Pediatric Health

ISSN: 2333-794X (Online)
Publisher: SAGE Publishing
Country of publisher: United States
LCC subjects: Medicine: Pediatrics
Website: https://journals.sagepub.com/home/gph

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