Rheumatic Heart Disease Burden

Stefan Milutinovic, MD; Marija Petrovic, MD, PhD; Aya Ziq, MS; Christian Sanchez, BS; Ahmed Sami Hammami, MD; Ricardo Orlando Escarcega, MD; Dustin Begosh-Mayne, MD; Malissa J. Wood, MD; Richard A. Chazal, MD; Juan C. Lopez-Mattei, MD

JACC: Advances (Dec 2024)

Rheumatic Heart Disease Burden

Stefan Milutinovic, MD,
Marija Petrovic, MD, PhD,
Aya Ziq, MS,
Christian Sanchez, BS,
Ahmed Sami Hammami, MD,
Ricardo Orlando Escarcega, MD,
Dustin Begosh-Mayne, MD,
Malissa J. Wood, MD,
Richard A. Chazal, MD,
Juan C. Lopez-Mattei, MD

Affiliations

Stefan Milutinovic, MD: Florida State University College of Medicine Internal Medicine Residency Program at Lee Health, Cape Coral, Florida, USA; Address for correspondence: Dr Stefan Milutinovic, Florida State University College of Medicine, Lee Health, 636 Del Prado Blvd S, Cape Coral, Florida 33990, USA.
Marija Petrovic, MD, PhD: Department of Cardiovascular Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Aya Ziq, MS: Nova Southeastern University Dr Kiran C Patel College of Osteopathic Medicine, Florida, USA
Christian Sanchez, BS: Nova Southeastern University Dr Kiran C Patel College of Osteopathic Medicine, Florida, USA
Ahmed Sami Hammami, MD: East Carolina University, Internal Medicine Department, Greenville, North Carolina, USA
Ricardo Orlando Escarcega, MD: Lee Health Heart Institute, Fort Myers, Florida, USA
Dustin Begosh-Mayne, MD: Florida State University College of Medicine Internal Medicine Residency Program at Lee Health, Cape Coral, Florida, USA
Malissa J. Wood, MD: Lee Health Heart Institute, Fort Myers, Florida, USA
Richard A. Chazal, MD: Lee Health Heart Institute, Fort Myers, Florida, USA
Juan C. Lopez-Mattei, MD: Lee Health Heart Institute, Fort Myers, Florida, USA

Journal volume & issue: Vol. 3, no. 12
p. 101393

Abstract

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Background: Rheumatic heart disease (RHD) is a major challenge to global health, primarily in low- and middle-income countries. Even though RHD is rare in high-income countries, it still poses a health challenge, yet there is a lack of data on its impact within the highest-income regions. Objectives: The purpose of this study was to compare the epidemiology of RHD in the United States of America (USA) and the European Union (EU). Methods: Data on RHD burden were collected using the Global Disease Burden Study 2021 using the Global Health Data Exchange query tool. Age-standardized rates of incidence (ASIR), prevalence (ASPR), death (ASDR), disability-adjusted life years (ASDALY), years lived with disability (ASYLD), and years of life lost (ASYLL) were collected. Estimated annual percentage change (EAPC) was calculated. Results: In USA in 2021, the ASPR was 123.4/100,000 with a decreasing annual trend of 0.32% since 1993. Between 2021 and 1993, the ASIR decreased from 10.6 to 10.0/100,000 cases. In the EU in 2021, the ASPR was 49.7/100,000 cases, with an annual decreasing trend of 1.6% between 2021 and 1993. Between 2021 and 1993, the ASIR decreased from 7.43 to 4.6/100,000 cases. The changing prevalence and incidence in the US was primarily driven by Florida, Nevada, and Tennessee. There has been a reversal in the burden of RHD since 2007 in the USA. In both regions, there was a significant gender disparity with female predominance. The EU reported higher age-standardized disability-adjusted life years and age-standardized years of life losts than the USA. Conclusions: The varied trends underscore the complexity of RHD epidemiology and the need for region-specific strategies to address this persistent health challenge.

Published in JACC: Advances

ISSN: 2772-963X (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system; Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid
Website: https://www.sciencedirect.com/journal/jacc-advances

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