Communications Biology (Dec 2021)

Hepatoprotective effects of Cassiae Semen on mice with non-alcoholic fatty liver disease based on gut microbiota

  • Hanyan Luo,
  • Hongwei Wu,
  • Lixia Wang,
  • Shuiming Xiao,
  • Yaqi Lu,
  • Cong Liu,
  • Xiankuo Yu,
  • Xiao Zhang,
  • Zhuju Wang,
  • Liying Tang

DOI
https://doi.org/10.1038/s42003-021-02883-8
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 13

Abstract

Read online

Luo, Wu, et al. assess the ability of Cassiae Semen and its extracted components to alleviate non-alcoholic fatty liver disease (NAFLD) in mice. In addition to reducing the symptoms of NAFLD, the authors find that Cassiae Semen modifies the gut microbiome of mice, and that its effects on the symptoms of NAFLD can also be conferred by fecal microbiome transfer.