Molbank (Dec 2020)

<i>N</i>-(2-(1<i>H</i>-Indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide

  • Stanimir Manolov,
  • Iliyan Ivanov,
  • Dimitar Bojilov

DOI
https://doi.org/10.3390/M1177
Journal volume & issue
Vol. 2021, no. 1
p. M1177

Abstract

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N-(2-(1H-Indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide was prepared by a reaction between tryptamine and flurbiprofen, applying N,N’-Dicyclohexylcarbodiimide, as a coupling agent. The obtained new amide has a fragment similar to Brequinar, a compound used in SARS-CoV-2 treatment trials. The newly synthesized compound was fully analyzed and characterized via 1H, 13C-NMR, UV, IR, and mass spectral data.

Keywords