Modern clinical-pharmaceutical approaches to the treatment of osteoarthrosis: role of combination drugs (chondroitin sulfate + glucosamine hydrochloride)

Abstract

The article reflects the current views on the etiology and pathogenesis of osteoarthrosis (OA), risk factors and clinical manifestations. Non-pharmacological and pharmacological approaches to the treatment of OA are demonstrated. The role of chondroprotectors in adjuvant therapy is emphasized; evidence-based data showing the efficacy of glucosamine sulfate and chondroitin sulfate in osteoarthritis is provided.

Keywords

• остеоартроз
• дегенерация суставного хряща
• симптом-модифицирующие препараты замедленного действия
• хондроитин
• глюкозамин
• osteoarthritis
• degeneration of articular cartilage
• slow-acting
• symptom-modifying drugs
• chondroitin sulfate
• glucosamine sulfate