Cardiovascular Therapeutics (Jan 2024)

Atorvastatin Attenuates Endothelial Cell Injury in Atherosclerosis Through Inhibiting ACSL4-Mediated Ferroptosis

  • Huilian Tan,
  • Ling Liu,
  • Yanchao Qi,
  • Dahong Zhang,
  • Yanchun Zhi,
  • Yu Li,
  • Huimin Zhang,
  • Jun Liu

DOI
https://doi.org/10.1155/2024/5522013
Journal volume & issue
Vol. 2024

Abstract

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Conclusion: Our findings suggest that ATV attenuates endothelial cell injury in AS by inhibiting ACSL4-mediated ferroptosis. These results provide insights into the potential therapeutic strategies for the treatment of AS.