Clinics and Practice (Aug 2022)

Severe Stenosis of Mitral Bioprosthetic Valve Thrombosis in a Patient with HCV-Related Cirrhosis and Duodenal Variceal Bleeding: The Deadly Triad

  • Rosangela Cocchia,
  • Salvatore Chianese,
  • Giovanni Lombardi,
  • Luigia Romano,
  • Valentina Capone,
  • Lucio Amitrano,
  • Raffaele Bennato,
  • Brigida Ranieri,
  • Giuseppe Russo,
  • Ciro Mauro,
  • Eduardo Bossone

DOI
https://doi.org/10.3390/clinpract12050071
Journal volume & issue
Vol. 12, no. 5
pp. 686 – 691

Abstract

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Bioprosthetic valve thrombosis (BPVT) is considered a relatively rare but life-threatening clinical entity. Thus, there is the need of high clinical suspicion in order to make a timely diagnosis and related appropriate therapeutic interventions. In this regard, the management of BPVT is high risk, whatever the option taken (surgery and/or systemic fibrinolysis). The presence of severe comorbidities—as decompensated cirrhosis—further complicates the clinical decision-making process, calling for a patient-tailored integrated multidisciplinary approach. We report a challenging case of a 45-year-old patient with mitral bioprosthetic valve thrombosis and hepatitis C virus (HCV)-related cirrhosis complicated by active duodenal variceal bleeding.

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