Medicina (Aug 2023)

Spindle Cell Rhabdomyosarcoma of the Inguinal Region Mimicking a Complicated Hernia in the Adult—An Unexpected Finding

  • Valentin Titus Grigorean,
  • Radu Serescu,
  • Andrei Anica,
  • Violeta Elena Coman,
  • Ştefan Iulian Bedereag,
  • Roxana Corina Sfetea,
  • Mircea Liţescu,
  • Iancu Emil Pleşea,
  • Costin George Florea,
  • Cosmin Burleanu,
  • Anwar Erchid,
  • Ionuţ Simion Coman

DOI
https://doi.org/10.3390/medicina59091515
Journal volume & issue
Vol. 59, no. 9
p. 1515

Abstract

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Rhabdomyosarcoma is a rare tumor that is diagnosed mostly in children and adolescents, rarely in adults, representing 2–5% of all soft tissue sarcomas. It has four subtypes that are recognized: embryonal (50%), alveolar (20%), pleomorphic (20%), and spindle cell/sclerosing (10%). The diagnosis of rhabdomyosarcoma is based on the histological detection of rhabdomyoblasts and the expression of muscle-related biomarkers. Spindle cell/sclerosing rhabdomyosarcoma consists morphologically of fusiform cells with vesicular chromatin arranged in a storiform pattern or long fascicles, with occasional rhabdomyoblasts. Also, dense, collagenous, sclerotic stroma may be seen more commonly in adults. We present a rare case of an adult who presented to the hospital with a tumor in the left inguinal area, was first diagnosed with a left strangulated inguinal hernia and was operated on as an emergency, although the diagnosis was ultimately a spindle cell rhabdomyosarcoma of the inguinal region.

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