Do liberal thresholds for red cell transfusion result in improved quality of life for patients undergoing intensive chemotherapy for acute myeloid leukemia? A randomized crossover feasibility study

• Suzy Morton,
• Mallika Sekhar,
• Heather Smethurst,
• Ana Mora,
• Renate L. Hodge,
• Cara L. Hudson,
• Joseph Parsons,
• Valerie Hopkins,
• Simon J. Stanworth

Affiliations

Suzy Morton

Department of Clinical Haematology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom. B15 2WB; Medical Department, NHS Blood and Transplant, Birmingham, United Kingdom. B15 2SG

Mallika Sekhar

Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom. NW1 2BU; Royal Free London NHS Foundation Trust, Department of Haematology, London, United Kingdom. NW3 2QG

Heather Smethurst

Clinical Trials Unit, NHS Blood and Transplant, Cambridge, United Kingdom. CB2 0PT

Ana Mora

Clinical Trials Unit, NHS Blood and Transplant, Cambridge, United Kingdom. CB2 0PT

Renate L. Hodge

Clinical Trials Unit, NHS Blood and Transplant, Cambridge,

Cara L. Hudson

Clinical Trials Unit, NHS Blood and Transplant, Bristol,

Joseph Parsons

Clinical Trials Unit, NHS Blood and Transplant, Bristol, United Kingdom. BS34 8RR

Valerie Hopkins

Clinical Trials Unit, NHS Blood and Transplant, Cambridge, United Kingdom. CB2 0PT

Simon J. Stanworth

Department of Clinical Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom. OX3 9BQ; Clinical Department, NHS Blood and Transplant, Oxford, United Kingdom. OX3 9BQ; Radcliffe Department of Medicine, University of Oxford, and NIHR Oxford Biomedical Research Centre