Sleep Science (Jun 2024)
The Relationship between Leptin Levels and Continuous Positive Airway Pressure Treatment: A Cluster Analysis
- Takashi Oki,
- Yutaka Kozu,
- Mamiko Hoshi,
- Yasunori Itoda,
- Naho Furusho,
- Ryosuke Ozoe,
- Yusuke Jinno,
- Akifumi Hirata,
- Yusuke Kurosawa,
- Shiho Yamada,
- Asami Fukuda,
- Mari Hikichi,
- Sotaro Shikano,
- Kenichi Sugaya,
- Hisato Hiranuma,
- Shuichiro Maruoka,
- Yasuhiro Gon
Affiliations
- Takashi Oki
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Yutaka Kozu
- ORCiD
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Mamiko Hoshi
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Yasunori Itoda
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Naho Furusho
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Ryosuke Ozoe
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Yusuke Jinno
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Akifumi Hirata
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Yusuke Kurosawa
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Shiho Yamada
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Asami Fukuda
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Mari Hikichi
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Sotaro Shikano
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Kenichi Sugaya
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Hisato Hiranuma
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Shuichiro Maruoka
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- Yasuhiro Gon
- Department of Internal Medicine, Division of Respiratory Medicine, School of Medicine, Nihon University, Itabashiku, Tokyo, Japan
- DOI
- https://doi.org/10.1055/s-0043-1777779
- Journal volume & issue
-
Vol. 17,
no. 02
pp. e143 – e150
Abstract
Objective Leptin is an appetite-suppressing hormone released by adipose tissue that plays an important role in severe obstructive sleep apnea syndrome (OSAS). However, it is unclear whether leptin levels are a useful biomarker for this syndrome. The present study aimed to assess the effect of continuous positive airway pressure (CPAP) treatment on the syndrome according to leptin levels, using a cluster classification based on clinical features of the syndrome.
Keywords