Sleep Science (Jun 2024)

The Relationship between Leptin Levels and Continuous Positive Airway Pressure Treatment: A Cluster Analysis

  • Takashi Oki,
  • Yutaka Kozu,
  • Mamiko Hoshi,
  • Yasunori Itoda,
  • Naho Furusho,
  • Ryosuke Ozoe,
  • Yusuke Jinno,
  • Akifumi Hirata,
  • Yusuke Kurosawa,
  • Shiho Yamada,
  • Asami Fukuda,
  • Mari Hikichi,
  • Sotaro Shikano,
  • Kenichi Sugaya,
  • Hisato Hiranuma,
  • Shuichiro Maruoka,
  • Yasuhiro Gon

DOI
https://doi.org/10.1055/s-0043-1777779
Journal volume & issue
Vol. 17, no. 02
pp. e143 – e150

Abstract

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Objective Leptin is an appetite-suppressing hormone released by adipose tissue that plays an important role in severe obstructive sleep apnea syndrome (OSAS). However, it is unclear whether leptin levels are a useful biomarker for this syndrome. The present study aimed to assess the effect of continuous positive airway pressure (CPAP) treatment on the syndrome according to leptin levels, using a cluster classification based on clinical features of the syndrome.

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