Communications Biology (Jul 2022)
Upregulation of OASIS/CREB3L1 in podocytes contributes to the disturbance of kidney homeostasis
- Yoshiaki Miyake,
- Masanori Obana,
- Ayaha Yamamoto,
- Shunsuke Noda,
- Koki Tanaka,
- Hibiki Sakai,
- Narihito Tatsumoto,
- Chihiro Makino,
- Soshi Kanemoto,
- Go Shioi,
- Shota Tanaka,
- Makiko Maeda,
- Yoshiaki Okada,
- Kazunori Imaizumi,
- Katsuhiko Asanuma,
- Yasushi Fujio
Affiliations
- Yoshiaki Miyake
- Laboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, Osaka University
- Masanori Obana
- Laboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, Osaka University
- Ayaha Yamamoto
- Laboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, Osaka University
- Shunsuke Noda
- Laboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, Osaka University
- Koki Tanaka
- Laboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, Osaka University
- Hibiki Sakai
- Laboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, Osaka University
- Narihito Tatsumoto
- Department of Nephrology, Graduate School of Medicine, Chiba University
- Chihiro Makino
- Department of Nephrology, Graduate School of Medicine, Chiba University
- Soshi Kanemoto
- Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima University
- Go Shioi
- Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research
- Shota Tanaka
- Laboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, Osaka University
- Makiko Maeda
- Laboratory of Clinical Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Osaka University
- Yoshiaki Okada
- Laboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, Osaka University
- Kazunori Imaizumi
- Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima University
- Katsuhiko Asanuma
- Department of Nephrology, Graduate School of Medicine, Chiba University
- Yasushi Fujio
- Laboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, Osaka University
- DOI
- https://doi.org/10.1038/s42003-022-03709-x
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 14
Abstract
Upregulation of transcription factor OASIS in podocytes contributes to podocyte and/or tubular injury through decreased PRKCi expression and is a critical event for the disturbance of kidney homeostasis.
