mSphere
(Aug 2021)
Evolutionary and Functional Analysis of Coagulase Positivity among the Staphylococci
Amy C. Pickering,
Gonzalo Yebra,
Xiangyu Gong,
Mariya I. Goncheva,
Bryan A. Wee,
Alison C. MacFadyen,
Lukas F. Muehlbauer,
Joana Alves,
Robyn A. Cartwright,
Gavin K. Paterson,
J. Ross Fitzgerald
Affiliations
Amy C. Pickering
ORCiD The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Gonzalo Yebra
The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Xiangyu Gong
The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Mariya I. Goncheva
ORCiD The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Bryan A. Wee
The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Alison C. MacFadyen
The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Lukas F. Muehlbauer
The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Joana Alves
The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Robyn A. Cartwright
The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Gavin K. Paterson
ORCiD The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
J. Ross Fitzgerald
ORCiD The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
DOI
https://doi.org/10.1128/mSphere.00381-21
Journal volume & issue
Vol. 6,
no. 4
Abstract
Read online
The ability of some species of staphylococci to promote coagulation of plasma is a key pathogenic and diagnostic trait. Here, we provide a comprehensive analysis of the coagulase positivity of the staphylococci and its evolutionary genetic basis.
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