Evolutionary and Functional Analysis of Coagulase Positivity among the Staphylococci

Amy C. Pickering; Gonzalo Yebra; Xiangyu Gong; Mariya I. Goncheva; Bryan A. Wee; Alison C. MacFadyen; Lukas F. Muehlbauer; Joana Alves; Robyn A. Cartwright; Gavin K. Paterson; J. Ross Fitzgerald

doi:10.1128/mSphere.00381-21

mSphere (Aug 2021)

Evolutionary and Functional Analysis of Coagulase Positivity among the Staphylococci

Amy C. Pickering,
Gonzalo Yebra,
Xiangyu Gong,
Mariya I. Goncheva,
Bryan A. Wee,
Alison C. MacFadyen,
Lukas F. Muehlbauer,
Joana Alves,
Robyn A. Cartwright,
Gavin K. Paterson,
J. Ross Fitzgerald

Affiliations

Amy C. Pickering: ORCiD; The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Gonzalo Yebra: The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Xiangyu Gong: The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Mariya I. Goncheva: ORCiD; The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Bryan A. Wee: The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Alison C. MacFadyen: The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Lukas F. Muehlbauer: The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Joana Alves: The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Robyn A. Cartwright: The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
Gavin K. Paterson: ORCiD; The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
J. Ross Fitzgerald: ORCiD; The Roslin Institute and Edinburgh Infectious Diseases, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom

DOI: https://doi.org/10.1128/mSphere.00381-21
Journal volume & issue: Vol. 6, no. 4

Abstract

Read online

The ability of some species of staphylococci to promote coagulation of plasma is a key pathogenic and diagnostic trait. Here, we provide a comprehensive analysis of the coagulase positivity of the staphylococci and its evolutionary genetic basis.

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

About the journal