Lean and Obese Zucker Rat Extensor Digitorum Longus Muscle high-frequency electrical stimulation (HFES) Data: Regulation of p70S6kinase Associated Proteins
Kevin M. Rice,
Anjaiah Katta,
Nandini D.P.K. Manne,
Ravikumar Arvapalli,
Gautam K. Ginjupalli,
Miaozong Wu,
Shinichi Asano,
Eric R. Blough
Affiliations
Kevin M. Rice
Center for Diagnostic Nanosystems, Marshall University, Huntington, WV, USA; Department of Internal Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, USA; Biotechnology Graduate Program West Virginia State University, Institute, WV, USA; Department of Health and Human Service, School of Kinesiology, Marshall University, Huntington, WV, USA; Correspondence to: Center for Diagnostic Nanosystems, Robert C. Byrd Biotechnology Science Center, Marshall University, Room 241D, 1700 3rd Ave., Huntington, WV 25755-1090, USA. Fax: +304 696 3766.
Anjaiah Katta
Center for Diagnostic Nanosystems, Marshall University, Huntington, WV, USA
Nandini D.P.K. Manne
Department of Public Heath, Marshall University, Huntington, WV, USA
Ravikumar Arvapalli
Center for Diagnostic Nanosystems, Marshall University, Huntington, WV, USA
Gautam K. Ginjupalli
Center for Diagnostic Nanosystems, Marshall University, Huntington, WV, USA
Miaozong Wu
College of Health, Science, and Technology, University of Central Missouri, Warrensburg, MO, USA
Shinichi Asano
School of Education, Health, and Human Performance, Fairmont State University, Fairmont, WV, USA
Eric R. Blough
Center for Diagnostic Nanosystems, Marshall University, Huntington, WV, USA; Biotechnology Graduate Program West Virginia State University, Institute, WV, USA; Department of Pharmaceutical Sciences and Research, School of Pharmacy, Marshall University, Huntington, WV, USA; Department of Pharmacology, Physiology and Toxicology, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, USA
Anaerobic exercise has been advocated as a prescribed treatment for the management of diabetes: however, alterations in exercise-induced signaling remain largely unexplored in the diabetic muscle. Here, we compare the basal and the in situ contraction-induced phosphorylation of the AKT, GSK3beta, mTor, p70s6K, Pten, and Shp2 in the lean and obese (fa/fa) Zucker rat Extensor Digitorum Longus (EDL) muscle following a single bout of contractile stimuli. This article represents data associated with prior publications from our lab (Katta et al., 2009a, 2009b; Tullgren et al., 1991) [1–3] and concurrent Data in Brief articles (Ginjupalli et al., 2017a, 2017b; Rice et al., 2017a, 2017b) [4–7]. Keywords: Diabetes, Skeletal muscle, High-frequency electrical stimulation (HFES), Zucker rat, Extensor Digitorum Longus, p70s6k
