Molbank
(Jan 2020)
(22<i>E</i>,24<i>S</i>)-24-Propylcholest-5en-3α-acetate: A New Steroid from the Stembark <i>Aglaia angustifolia</i> (Miq.) (Meliaceae)
Ricson P. Hutagaol,
Desi Harneti,
Ace T. Hidayat,
Nurlelasari,
Rani Maharani,
Dewa Gede Katja,
Unang Supratman,
Khalijah Awang,
Yoshihito Shiono
Affiliations
Ricson P. Hutagaol
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Nusa Bangsa University, Bogor 16166, West Java, Indonesia
Desi Harneti
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia
Ace T. Hidayat
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia
Nurlelasari
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia
Rani Maharani
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia
Dewa Gede Katja
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Sam Ratulangi, Kampus Bahu, Manado 95115, North Sulawesi, Indonesia
Unang Supratman
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia
Khalijah Awang
Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 59100, Malaysia
Yoshihito Shiono
Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997-8555, Japan
DOI
https://doi.org/10.3390/M1112
Journal volume & issue
Vol. 2020,
no. 1
Abstract
Read online
A new propylcholesterol-type steroid, namely (22E,24S)-24-propylcholest-5en-3α-acetate (1), has been isolated from the stembark of Aglaia angustifolia (Miq.). The structure of 1 was determined on the basis of spectroscopic data including 1D- and 2D-NMR as well as high resolution mass spectroscopy analysis. Compound 1 showed weak activity against the MCF-7 breast cancer cell line.
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