Research progress on pharmacological properties and application of probiotics in the fermentation of Scutellaria baicalensis Georgi

Fangyu Guo; Fangyu Guo; Chunhai Li; Jiaxin Dou; Jiaxin Dou; Jie Liang; Jie Liang; Zouquan Chen; Zouquan Chen; Zhenshang Xu; Zhenshang Xu; Ting Wang; Ting Wang

doi:10.3389/fnut.2024.1407182

Frontiers in Nutrition (Jun 2024)

Research progress on pharmacological properties and application of probiotics in the fermentation of Scutellaria baicalensis Georgi

Fangyu Guo,
Fangyu Guo,
Chunhai Li,
Jiaxin Dou,
Jiaxin Dou,
Jie Liang,
Jie Liang,
Zouquan Chen,
Zouquan Chen,
Zhenshang Xu,
Zhenshang Xu,
Ting Wang,
Ting Wang

Affiliations

Fangyu Guo: State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Fangyu Guo: School of Bioengineering, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Chunhai Li: Department of Radiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China
Jiaxin Dou: State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Jiaxin Dou: School of Bioengineering, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Jie Liang: State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Jie Liang: School of Bioengineering, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Zouquan Chen: State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Zouquan Chen: School of Bioengineering, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Zhenshang Xu: State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Zhenshang Xu: School of Bioengineering, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Ting Wang: State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Science, Jinan, China
Ting Wang: School of Bioengineering, Qilu University of Technology, Shandong Academy of Science, Jinan, China

DOI: https://doi.org/10.3389/fnut.2024.1407182
Journal volume & issue: Vol. 11

Abstract

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Scutellaria baicalensis Georgi is a medicinal herb with a rich history of use in traditional Chinese medicine. This review concentrates on the chemical constituents of Scutellaria baicalensis Georgi, with a particular emphasis on flavonoids such as baicalin, baicalein, and wogonin. Additionally, it examines the effects of probiotic fermentation on the plant’s chemical profile and pharmacological actions. Evidence suggests that probiotic fermentation markedly modifies the bioactive components of Scutellaria baicalensis Georgi, thereby augmenting its medicinal potency. The paper delves into the mechanisms by which the primary active constituents of Scutellaria baicalensis Georgi are altered during fermentation and how these changes influence its pharmacological properties. This review aims to lay a theoretical groundwork for the clinical utilization of Scutellaria baicalensis Georgi and the formulation of innovative therapeutic approaches.

Published in Frontiers in Nutrition

ISSN: 2296-861X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Technology: Home economics: Nutrition. Foods and food supply
Website: https://www.frontiersin.org/journals/nutrition/

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