Advanced Science (Nov 2021)

Nanotechnology for Targeted Detection and Removal of Bacteria: Opportunities and Challenges

  • Mohammad J. Hajipour,
  • Amir Ata Saei,
  • Edward D. Walker,
  • Brian Conley,
  • Yadollah Omidi,
  • Ki‐Bum Lee,
  • Morteza Mahmoudi

DOI
https://doi.org/10.1002/advs.202100556
Journal volume & issue
Vol. 8, no. 21
pp. n/a – n/a

Abstract

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Abstract The emergence of nanotechnology has created unprecedented hopes for addressing several unmet industrial and clinical issues, including the growing threat so‐termed “antibiotic resistance” in medicine. Over the last decade, nanotechnologies have demonstrated promising applications in the identification, discrimination, and removal of a wide range of pathogens. Here, recent insights into the field of bacterial nanotechnology are examined that can substantially improve the fundamental understanding of nanoparticle and bacteria interactions. A wide range of developed nanotechnology‐based approaches for bacterial detection and removal together with biofilm eradication are summarized. The challenging effects of nanotechnologies on beneficial bacteria in the human body and environment and the mechanisms of bacterial resistance to nanotherapeutics are also reviewed.

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