Ligand-Free BaF2: Nd Nanoparticles With Low Cytotoxicity, High Stability and Enhanced Fluorescence Intensity as NIR-II Imaging Probes

Xiaoxia Cui; Xiaoxia Cui; Yantao Xu; Yantao Xu; Shengfei She; Shengfei She; Xusheng Xiao; Xusheng Xiao; Chaoqi Hou; Chaoqi Hou; Haitao Guo; Haitao Guo

doi:10.3389/fphy.2021.665956

Frontiers in Physics (May 2021)

Ligand-Free BaF2: Nd Nanoparticles With Low Cytotoxicity, High Stability and Enhanced Fluorescence Intensity as NIR-II Imaging Probes

Xiaoxia Cui,
Xiaoxia Cui,
Yantao Xu,
Yantao Xu,
Shengfei She,
Shengfei She,
Xusheng Xiao,
Xusheng Xiao,
Chaoqi Hou,
Chaoqi Hou,
Haitao Guo,
Haitao Guo

Affiliations

Xiaoxia Cui: State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Science (CAS), Xi'an, China
Xiaoxia Cui: Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, China
Yantao Xu: State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Science (CAS), Xi'an, China
Yantao Xu: Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, China
Shengfei She: State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Science (CAS), Xi'an, China
Shengfei She: Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, China
Xusheng Xiao: State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Science (CAS), Xi'an, China
Xusheng Xiao: Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, China
Chaoqi Hou: State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Science (CAS), Xi'an, China
Chaoqi Hou: Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, China
Haitao Guo: State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Science (CAS), Xi'an, China
Haitao Guo: Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences (UCAS), Beijing, China

DOI: https://doi.org/10.3389/fphy.2021.665956
Journal volume & issue: Vol. 9

Abstract

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Ligand-free BaF2:Nd nanoparticles (NPs) with a size of 10 nm were fabricated by a novel synthetic route in the liquid phase. A transparent dispersion of the BaF2:Nd NPs mixed with propanetriol and DMSO-d6 was done. Highly stable and outstanding near-infrared (NIR) fluorescence centered at 1,058 nm was detected using an excitation wavelength of 808 nm laser. Moreover, the dispersion can be found to be stable for over 1 month, and the cytotoxicity of the BaF2:Nd NP dispersion has also been studied by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. The superior performance of these NPs exhibits their great potential application in high-contrast and high-penetration in vivo imaging.

Published in Frontiers in Physics

ISSN: 2296-424X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Science: Physics
Website: https://www.frontiersin.org/journals/physics

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