Direct observation of independently moving replisomes in Escherichia coli

Aleksandre Japaridze; Christos Gogou; Jacob W. J. Kerssemakers; Huyen My Nguyen; Cees Dekker

doi:10.1038/s41467-020-16946-7

Nature Communications (Jun 2020)

Direct observation of independently moving replisomes in Escherichia coli

Aleksandre Japaridze,
Christos Gogou,
Jacob W. J. Kerssemakers,
Huyen My Nguyen,
Cees Dekker

Affiliations

Aleksandre Japaridze: Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology
Christos Gogou: Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology
Jacob W. J. Kerssemakers: Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology
Huyen My Nguyen: Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology
Cees Dekker: Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology

DOI: https://doi.org/10.1038/s41467-020-16946-7
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 10

Abstract

Read online

How chromosome replication and segregation is organised in E. coli is a matter of debate. Here the authors visualise the bacterial chromosome and the replisomes during DNA replication, providing support for a previously suggested train track model.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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