Respiratory Medicine Case Reports (Jan 2023)

Minoxidil-induced lung disease, masquerading as hypersensitivity pneumonitis

  • Daisuke Takekosh,
  • Teruhisa Nemoto,
  • Susumu Saito,
  • Yuma Matsui,
  • Shunsuke Minagawa,
  • Hiromichi Hara,
  • Takanori Numata,
  • Jun Araya,
  • Kazuyoshi Kuwano

Journal volume & issue
Vol. 43
p. 101861

Abstract

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We report the case of a 71-year-old male with essential thrombosis who presented with ground-glass lung opacity with a mosaic pattern on computed tomography, which resolved spontaneously with hospitalization. This was confused with a case of hypersensitivity pneumonitis (HP), which later turned out to be a drug-induced lung disease caused by surreptitiously administered minoxidil. This case emphasizes the importance of obtaining a correct medication history to make an accurate diagnosis, and this is the first report of minoxidil causing HP-like pulmonary illness.

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