MONOCLONAL ANTIBODY FOR MULTIPLE SCLEROSIS TREATMENT

Abstract

Monoclonal antibodies are widely used in various fields of modern medicine, for example, in oncology, rheumatology, gastroenterology, transplantation. Since beginning of this century monoclonal antibodies began to be explored for the treatment of multiple sclerosis (MS). From this period monoclonal antibody also actively introduced in pathogenetic therapy of MS. In this review, we discuss the findings of clinical trials already registered monoclonal antibodies in the Russian Federation, such as Natalizumab and Alemtuzumab.

Keywords

• disseminated sclerosis
• drugs changing the course of ds (dccds)
• monoclonal antibodies
• natalizumab
• alemtuzumab