Linked Toll-Like Receptor Triagonists Stimulate Distinct, Combination-Dependent Innate Immune Responses

• Tyler J. Albin,
• Janine K. Tom,
• Saikat Manna,
• Adrienne P. Gilkes,
• Samuel A. Stetkevich,
• Benjamin B. Katz,
• Medalyn Supnet,
• Jiin Felgner,
• Aarti Jain,
• Rie Nakajima,
• Algis Jasinskas,
• Albert Zlotnik,
• Eric Pearlman,
• D. Huw Davies,
• Phillip L. Felgner,
• Amanda M. Burkhardt,
• Aaron P. Esser-Kahn

Affiliations

Tyler J. Albin

Department of Chemistry, University of California, Irvine, California, United States

Janine K. Tom

Department of Chemistry, University of California, Irvine, California, United States

Saikat Manna

Department of Chemistry, University of California, Irvine, California, United States

Adrienne P. Gilkes

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

Samuel A. Stetkevich

Department of Chemistry, University of California, Irvine, California, United States

Benjamin B. Katz

Department of Chemistry, University of California, Irvine, California, United States

Medalyn Supnet

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

Jiin Felgner

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

Aarti Jain

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

Rie Nakajima

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

Algis Jasinskas

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

Albert Zlotnik

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

Eric Pearlman

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

D. Huw Davies

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

Phillip L. Felgner

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

Amanda M. Burkhardt

Vaccine Research and Development Center, Department of Physiology & Biophysics, University of California, Irvine, California, United States

Aaron P. Esser-Kahn

Department of Chemistry, University of California, Irvine, California, United States