Nature Communications (Jan 2019)

Alveolar proteins stabilize cortical microtubules in Toxoplasma gondii

  • Clare R. Harding,
  • Matthew Gow,
  • Joon Ho Kang,
  • Emily Shortt,
  • Scott R. Manalis,
  • Markus Meissner,
  • Sebastian Lourido

DOI
https://doi.org/10.1038/s41467-019-08318-7
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 14

Abstract

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Cortical microtubules of Toxoplasma gondii are exceptionally stable, but it isn’t known how they are anchored along membranes. Here, Harding et al. show that GAPM proteins localize to the inner membrane complex and are essential for maintaining the structural stability of parasites.