Biosynthetic Crossover of 5‑Lipoxygenase and Cyclooxygenase‑2 Yields 5‑Hydroxy-PGE2 and 5‑Hydroxy-PGD2
Fumie Nakashima,
Takashi Suzuki,
Odaine N. Gordon,
Dominic Golding,
Toshiaki Okuno,
Juan A. Giménez-Bastida,
Takehiko Yokomizo,
Claus Schneider
Affiliations
Fumie Nakashima
Division of Clinical Pharmacology, Department of Pharmacology, and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical School, Nashville, Tennessee, United States
Takashi Suzuki
Division of Clinical Pharmacology, Department of Pharmacology, and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical School, Nashville, Tennessee, United States
Odaine N. Gordon
Division of Clinical Pharmacology, Department of Pharmacology, and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical School, Nashville, Tennessee, United States
Dominic Golding
Division of Clinical Pharmacology, Department of Pharmacology, and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical School, Nashville, Tennessee, United States
Toshiaki Okuno
Department of Biochemistry, Juntendo University Graduate School of Medicine, Tokyo, Japan
Juan A. Giménez-Bastida
Division of Clinical Pharmacology, Department of Pharmacology, and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical School, Nashville, Tennessee, United States
Takehiko Yokomizo
Department of Biochemistry, Juntendo University Graduate School of Medicine, Tokyo, Japan
Claus Schneider
Division of Clinical Pharmacology, Department of Pharmacology, and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical School, Nashville, Tennessee, United States