Revista da Sociedade Brasileira de Medicina Tropical (Jul 2021)

SARS-CoV-2 nucleic acid shedding is variable for every person

  • Daiana de Lima-Morales,
  • Priscila Lamb Wink,
  • Fabiana Caroline Zempulski Volpato,
  • Joíza Lins Camargo,
  • Fernanda de-Paris,
  • Afonso Luís Barth

DOI
https://doi.org/10.1590/0037-8682-0162-2021
Journal volume & issue
Vol. 54

Abstract

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Abstract INTRODUCTION: Considering the persistent positivity on RT-qPCR tests, the results of SARS-CoV-2 were monitored to evaluate the viral RNA shedding period. METHODS: Between March and June 2020, the sequential results of 29 healthcare workers’ were monitored using RT-qPCR. RESULTS: More than 50% of the individuals remained RT-qPCR positive after 14 days. Furthermore, this is the first study to describe positive RT-qPCR for SARS-CoV-2 in a healthcare worker with mild symptoms 95 days after the first positive test. CONCLUSIONS: Sequential RT-qPCR results were heterogeneous, and the viral RNA shedding period is unique for each person.

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