Emerging Infectious Diseases (Oct 2024)

Genomic Epidemiology of Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae in Kenya, Uganda, and Jordan

  • Denis K. Byarugaba,
  • Tamer S. Osman,
  • Omar M. Sayyouh,
  • Godfrey Wokorach,
  • Collins K. Kigen,
  • James W. Muturi,
  • Vanessa N. Onyonyi,
  • Mayar M. Said,
  • Salwa A. Nasrat,
  • Mahmoud Gazo,
  • Bernard Erima,
  • Stephen Alafi,
  • Hope O. Kabatesi,
  • Fred Wabwire-Mangen,
  • Hannah Kibuuka,
  • Anjali P. Sapre,
  • Katelyn V. Bartlett,
  • Francois Lebreton,
  • Melissa J. Martin,
  • Evelyn W. Mahugu,
  • Hunter J. Smith,
  • Lillian A. Musila

DOI
https://doi.org/10.3201/eid3014.240370
Journal volume & issue
Vol. 30, no. 14
pp. 33 – 40

Abstract

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Surveillance of antimicrobial resistance in Kenya, Uganda, and Jordan identified multidrug-resistant high-risk bacterial clones: Escherichia coli sequence types 131, 1193, 69, 167, 10, 648, 410, 405 and Klebsiella pneumoniae sequence types 14, 147, 307, 258. Clones emerging in those countries exhibited high resistance mechanism diversity, highlighting a serious threat for multidrug resistance.

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