Talanta Open (Aug 2024)

Recent update on biomimetic sensor technology for cancer diagnosis

  • Priyanku Pradip Das,
  • Rupak Nagraik,
  • Avinash Sharma,
  • Tarun Kumar Upadhyay,
  • H. Lalhlenmawia,
  • Deepak Balram,
  • Kuang-Yow Lian,
  • Jay Singh,
  • Deepak Kumar

Journal volume & issue
Vol. 9
p. 100276

Abstract

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Biomimetic sensors are devices that replicate biological receptors and enzymes with extraordinary accuracy and sensitivity by taking their cues from nature's effective mechanisms. They enable quick diagnosis and better treatment options by providing non-invasive detection of cancer-specific biomarkers in physiological fluids. This review addresses numerous optical and electronic biomimetic sensor types and emphasizes the benefits of their usage in cancer diagnostics. Some of the recognition components used in biomimetic sensors are aptamers, molecularly imprinted polymers (MIPs), and immunomimetic sensors. The widespread use of biomimetic sensors for cancer diagnostics has promise despite obstacles like specificity and cost-effectiveness. The use of wearable technology and artificial intelligence improves individualized cancer management even further. The overall objective of this review is to comprehensively explore the field of biomimetics sensors in the context of cancer diagnostics, highlighting their various types and recognition components and to emphasize on the significant benefits of biomimetics sensors, such as their accuracy and sensitivity, in enabling non-invasive detection of cancer-specific biomarkers. Overall, biomimetic sensors are a revolutionary development that advances our understanding of early cancer detection, improved patient outcomes, and enhanced healthcare.

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