Heart failure with preserved ejection fraction. Can we improve the prognosis of our patients?

Abstract

HF with preserved EF is defined as HF with left ventricular EF ≥ 50%. Patients with slightly impaired EF, between 41 and 49%, are usually considered together with EF ≥ 50% in randomized studies. Unlike HF with depressed EF (≤40%) in which different interventions (neurohormonal antagonists, electrical therapy) have been shown to improve prognosis, until recently we did not have evidence from a randomized study in the context of EF >40%. Practice guidelines generally recommended evaluating the etiology, considering comorbidities, and controlling accompanying conditions (heart rate, blood pressure, atrial fibrillation, ischemia). In the subgroup of patients with EF between 41% and 49%, there was a IIb indication for neurohormonal antagonists in the 2021 ESC HF guideline. (1)

Keywords

• insuficiencia cardíaca
• fracción de eyección