Journal of Feline Medicine and Surgery Open Reports (Jul 2020)

Diagnosis and clinical outcome following surgical resection of an intracranial grade III anaplastic gemistocytic astrocytoma in a cat

  • Vishal D Murthy,
  • Molly L Liepnieks,
  • Melissa A Roy,
  • Kevin D Woolard,
  • Beverly K Sturges,
  • Chai-Fei Li

DOI
https://doi.org/10.1177/2055116920939479
Journal volume & issue
Vol. 6

Abstract

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Case summary A 10-year-old Maine Coon cat was presented for acute onset seizures and cerebrothalamic signs. An intracranial mass, suspected to be a meningioma, was diagnosed on MRI and surgically excised. Histopathology appeared consistent with an atypical meningioma. However, following rapid regrowth of the neoplasm, the patient was humanely euthanized 3 months later. On post-mortem histopathology, the neoplasm was diagnosed as a grade III anaplastic gemistocytic astrocytoma. Relevance and novel information Gemistocytic astrocytomas are rare brain tumors in the feline patient. This case represents the first report of a feline grade III anaplastic gemistocytic astrocytoma in the cerebrum of a cat with surgical excision and recurrence. The challenging nature of ante-mortem diagnosis and the guarded prognosis, despite surgical intervention, are presented in this report.