Medical Mycology Case Reports (Jun 2017)

Coccidioidal meningitis complicated by central nervous system vasculitis in a patient with leukemia

  • Dany Tager,
  • Anne Hatch,
  • Jennifer Segar,
  • Brentin Roller,
  • Mayar Al Mohajer,
  • Tirdad T. Zangeneh

DOI
https://doi.org/10.1016/j.mmcr.2017.03.003
Journal volume & issue
Vol. 16, no. C
pp. 8 – 11

Abstract

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Central Nervous System (CNS) vasculitis is the most common life-threatening complication of coccidioidal meningitis. It is manifested by cerebral ischemia, hemorrhage, and infarction. We report a case of CNS vasculitis in a patient receiving chemotherapy and review of the literature on coccidioidal meningitis. The patient was treated with combination antifungal therapy and a short course of high dose corticosteroids with a modest improvement in her neurological examination after initiation of steroids.

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