Nature Communications (Feb 2021)

PlasmidHawk improves lab of origin prediction of engineered plasmids using sequence alignment

  • Qi Wang,
  • Bryce Kille,
  • Tian Rui Liu,
  • R. A. Leo Elworth,
  • Todd J. Treangen

DOI
https://doi.org/10.1038/s41467-021-21180-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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Advances in synthetic biology and genome engineering raise awareness of potential misuse. Here, the authors present PlasmidHawk, a sequence alignment based method for lab-of-origin prediction.