Thyroid status of conditionally healthy pregnant women in Baku.

Abstract

Introduction The conducted research examined the thyroid status of conditionally healthy pregnant women in the city of Baku. Materials and Methods To achieve the objective of the study, based on the devel- oped clinical and laboratory criteria, 48 conditionally healthy pregnant women in the 1st trimester of pregnancy aged 18–35 years (average age 26.5±4.4 years) were se- lected for the period from 2021 to 2023 and underwent examination at the surgical clinic of the Azerbaijan Med- ical University. Results The average gestational age at the time of examination was 9.9 weeks. In the structure of thyroid pathology in conditionally healthy pregnant women, subclinical hypo- thyroidism predominated (10 women; 20.8%). In 16.7% of cases (8 women), an increase in the AT-TPO level was observed. Gestational subclinical thyrotoxicosis was de- tected in 3 pregnant women (6.25%). Diffuse goiter was detected in 2 pregnant women (4.16%). And in 1 case each, nodular goiter (2.08%) and manifest hypothyroid- ism (2.08%) were detected. Conclusion Considering the high prevalence of subclinical hypothy- roidism based on the results of continuous screening of healthy women without a history of thyroid pathology, it confirms the need to include TSH testing in the 1st trimester for all pregnant women, and in the case of its excess of ≥2.5 mIU/L, it is recommended to determine free T4 and AT-TPO for early diagnosis and timely ad- ministration of replacement therapy.

Keywords

• thyroid status
• thyroid gland
• pathology
• pregnant women
• thyroid stimulating hormone
• free fraction of thyroxine traumatic cataract
• demographic and clinical characteristics