PCR Detection of Viral Nucleic Acid in Fatal Asthma: Is the Lower Respiratory Tract a Reservoir for Common Viruses?

Vasilija Macek; Azzeddine Dakhama; James C Hogg; Francis HY Green; Bruce K Rubin; Richard G Hegele

doi:10.1155/1999/938049

Canadian Respiratory Journal (Jan 1999)

PCR Detection of Viral Nucleic Acid in Fatal Asthma: Is the Lower Respiratory Tract a Reservoir for Common Viruses?

Vasilija Macek,
Azzeddine Dakhama,
James C Hogg,
Francis HY Green,
Bruce K Rubin,
Richard G Hegele

Affiliations

Vasilija Macek: McDonald Research Laboratories, St Paul’s Hospital, Vancouver, British Columbia, Canada
Azzeddine Dakhama: McDonald Research Laboratories, St Paul’s Hospital, Vancouver, British Columbia, Canada
James C Hogg: McDonald Research Laboratories, St Paul’s Hospital, Vancouver, British Columbia, Canada
Francis HY Green: Department of Pathology, University of Calgary, Calgary, Alberta, Canada
Bruce K Rubin: Departments of Pediatrics, Medicine, Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
Richard G Hegele: McDonald Research Laboratories, St Paul’s Hospital, Vancouver, British Columbia, Canada

DOI: https://doi.org/10.1155/1999/938049
Journal volume & issue: Vol. 6, no. 1
pp. 37 – 43

Abstract

Read online

BACKGROUND: There is indirect evidence implicating viral respiratory tract infections in the pathogenesis of fatal asthma. However, it is unknown whether viruses are present within the lower respiratory tract in fatal asthma.

Published in Canadian Respiratory Journal

ISSN: 1198-2241 (Print); 1916-7245 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: https://onlinelibrary.wiley.com/journal/7503

About the journal