Chemosensors (May 2023)

Modeling and Simulation of a TFET-Based Label-Free Biosensor with Enhanced Sensitivity

  • Sagarika Choudhury,
  • Krishna Lal Baishnab,
  • Koushik Guha,
  • Zoran Jakšić,
  • Olga Jakšić,
  • Jacopo Iannacci

DOI
https://doi.org/10.3390/chemosensors11050312
Journal volume & issue
Vol. 11, no. 5
p. 312

Abstract

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This study discusses the use of a triple material gate (TMG) junctionless tunnel field-effect transistor (JLTFET) as a biosensor to identify different protein molecules. Among the plethora of existing types of biosensors, FET/TFET-based devices are fully compatible with conventional integrated circuits. JLTFETs are preferred over TFETs and JLFETs because of their ease of fabrication and superior biosensing performance. Biomolecules are trapped by cavities etched across the gates. An analytical mathematical model of a TMG asymmetrical hetero-dielectric JLTFET biosensor is derived here for the first time. The TCAD simulator is used to examine the performance of a dielectrically modulated label-free biosensor. The voltage and current sensitivity of the device and the effects of the cavity size, bioanalyte electric charge, fill factor, and location on the performance of the biosensor are also investigated. The relative current sensitivity of the biosensor is found to be about 1013. Besides showing an enhanced sensitivity compared with other FET- and TFET-based biosensors, the device proves itself convenient for low-power applications, thus opening up numerous directions for future research and applications.

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