Advanced Science (Nov 2024)

Highly Sensitive Perovskite Photoplethysmography Sensor for Blood Glucose Sensing Using Machine Learning Techniques

  • Yongjian Zheng,
  • Zhenye Zhan,
  • Qiulan Chen,
  • Jianxin Chen,
  • Jianwen Luo,
  • Juntao Cai,
  • Yang Zhou,
  • Ke Chen,
  • Weiguang Xie

DOI
https://doi.org/10.1002/advs.202405681
Journal volume & issue
Vol. 11, no. 43
pp. n/a – n/a

Abstract

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Abstract Accurate non‐invasive monitoring of blood glucose (BG) is a challenging issue in the therapy of diabetes. Here near‐infrared (NIR) photoplethysmography (PPG) sensor based on a vapor‐deposited mixed tin‐lead hybrid perovskite photodetector is developed. The device shows a high detectivity of 5.32 × 1012 Jones and a large linear dynamic range (LDR) of 204 dB under NIR light, guaranteeing accurate extraction of eleven features from the PPG signal. By a combination of machine learning, accurate prediction of blood glucose level with mean absolute relative difference (MARD) as small as 2.48% is realized. The self‐powered PPG sensor also works for real‐time outdoor healthcare monitors using sunlight as a light source. The potential for early diabetes diagnoses by the perovskite PPG sensor is demonstrated.

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