Tanshinones: First-in-Class Inhibitors of the Biogenesis of the Type 3 Secretion System Needle of Pseudomonas aeruginosa for Antibiotic Therapy

• Chao Feng,
• Yinong Huang,
• Wangxiao He,
• Xiyao Cheng,
• Huili Liu,
• Yongqi Huang,
• Bohan Ma,
• Wei Zhang,
• Chongbing Liao,
• Weihui Wu,
• Yongping Shao,
• Dan Xu,
• Zhengding Su,
• Wuyuan Lu

Affiliations

Chao Feng

†Center for Translational Medicine, Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an, China

Yinong Huang

‡Shaanxi Institute of Pediatric Diseases, Affiliated Children’s Hospital, Xi’an Jiaotong University, Xi’an, China

Wangxiao He

§Key Laboratory of Biomedical Information Engineering of the Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, China

Xiyao Cheng

Department of Biological and Food Engineering, Hubei University of Technology, Wuhan, China

Huili Liu

State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, China

Yongqi Huang

Department of Biological and Food Engineering, Hubei University of Technology, Wuhan, China

Bohan Ma

†Center for Translational Medicine, Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an, China

Wei Zhang

§Key Laboratory of Biomedical Information Engineering of the Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, China

Chongbing Liao

†Center for Translational Medicine, Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an, China

Weihui Wu

State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China

Yongping Shao

†Center for Translational Medicine, Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an, China

Dan Xu

§Key Laboratory of Biomedical Information Engineering of the Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, China

Zhengding Su

Department of Biological and Food Engineering, Hubei University of Technology, Wuhan, China

Wuyuan Lu

Institute of Human Virology and Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, United States