Annals of Clinical and Translational Neurology (Aug 2025)

Paroxysmal Dyskinesias Secondary to HHV‐6A Encephalitis: The First Case Report and Literature Review

  • Zhuoran Wang,
  • Haiting Li,
  • Xiaoping Du,
  • Qiong Wang,
  • Yating Zhang,
  • Huifang Wang

DOI
https://doi.org/10.1002/acn3.70110
Journal volume & issue
Vol. 12, no. 8
pp. 1717 – 1722

Abstract

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ABSTRACT Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias. We present a case of paroxysmal kinesigenic dyskinesias secondary to human herpesvirus 6A encephalitis for the first time, and review the literature on paroxysmal dyskinesias secondary to central nervous system infection. This case highlights the importance of differentiating primary from secondary paroxysmal dyskinesias. Early anti‐infection and immunotherapy may be the key to treating this type of disease.

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